Can I drink alcohol with Sertraline?

Question

Hello, I have been taking sertraline since October. I am now at 150 mg. I was told to avoid alcohol as much as possible since it is dangerous, but they did not explain the dangers except the fact that the medication will not work as well. Since it is the holiday season and I am also going south on December 30th. I risk consuming more alcohol for the next 2 weeks exceptionally. Yes, I am aware of all the risks that you have mentioned, which is why I do not normally drink alcohol. However, I would like to know if I temporarily deviate from my good habits during the next 2 weeks (in relation to alcohol) and will I put my life in danger? Is it possible to overdose for example? Or if I consume alcohol for the next two weeks (the holidays and my trip) I will indeed experience side effects as mentioned above without necessarily putting my life in danger! Thank you

Naji-tom Samaha · Accepted Answer

Good morning, ma'am, It is indeed strongly recommended not to consume alcohol with this medication. First, alcohol can worsen depressive and anxiety symptoms, even with small amounts. Alcohol can also worsen the side effects experienced, such as dizziness, drowsiness, and nausea. Alcohol can also decrease the quality of sleep, which in turn can worsen or trigger anxiety or depressive symptoms. People with mood disorders such as anxiety or depression are at much higher risk for substance use disorders, including alcohol. Alcohol can impair judgment and this can be amplified in the presence of anxiety or depressive symptoms. I would also like to point out, in general, that alcohol consumption is associated with a negative impact on physical, mental and psychological health. Alcohol use may be occasional, such as 1-2 drinks, but it is still at your own risk. Sincerely, Tom Samaha, pharmacist I it is impossible to determine the effects of alcohol consumption on every person, but consumption for 2 weeks is unlikely to be beneficial and more likely to cause the problems I mentioned above. You report that I did not mention any danger to your life but this was clearly described in my response: possible exacerbation of anxiety symptoms or depression, sleep and mood disturbance, impulsivity. Given the risks and lack of benefits of alcohol consumption, the answer is clear. All in all, I wish you a merry Christmas and a safe journey :) Sincerely, Tom Samaha, pharmacist