Can a kidney function result be reversed?

Question

I received a result of 88 on the CKD-EPI test, which would correspond to the first stage of renal failure between 60 and 89... I am very surprised, I don't have diabetes, no high blood pressure, I don't smoke, I am active. However, at the time I took the blood test, I was taking anti-inflammatory drugs, could this explain the results? My creatine level is 69 (39-91) and albumin 41 (24-46), the rest is normal calcium, potassium, ALT, chloride. Hello, Thank you for your quick answer. So, if I were to take another blood test without NSAIDs, how long would I have to be without taking them before taking the blood test again and making sure that the creatine is not affected? Days, weeks? What if that was what caused the creatinine to go up, which would have skewed the CKD-EPI result, so it could be an "episodic" result and not permanent? Thank you!

Naji-tom Samaha · Accepted Answer

Hello ma'am, taking a non-steroidal anti-inflammatory drug can increase the serum creatine value, which is a value used in the CKD-EPI equation. Just to reassure you further, this equation is an estimate, and without having any other information than what you have provided, I see no reason to worry. Indeed, there is little that can be deduced or worked out with a single value. 1 to 2 weeks after stopping the anti-inflammatory should be sufficient. However, if you have pain, you should not 'burn out' on this option, especially if it is effective and well tolerated for you! For the second question, if it is the medication that is causing an increase, it may indeed be episodic. Sincerely, Tom Samaha, pharmacist