Are Omeprazole and clonazepam safe for breastfeeding?

39-year-old woman5 years ago
Hello! I have 2 good questions for you! During my pregnancy I was prescribed omeprazole to replace my pantoprazole for my acid reflux. I have now given birth and am breastfeeding my baby. I was wondering if my omeprazole could be dangerous for the baby... if so, what could I get to replace it with? Also, I have a prescription for clonazepam that I was taking for anxiety before my pregnancy. I didn't take it during my pregnancy because I was told it wasn't good for the baby. Now that I've given birth, I was wondering if there were any contraindications with breastfeeding? I have started to experience intense anxiety again since my delivery .... If it is not advisable to breastfeed, is there a medication I can take occasionally for my anxiety that is compatible with breastfeeding? Thank you for your answer!!!
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Sami Soltan · 5 years ago
Good evening, Omeprazole is indeed the first-line PPI for women of childbearing age, for those planning a pregnancy or when treatment is required during pregnancy. Its use is safe in breastfeeding and supported by a few studies with an unlikely risk of adverse effects in the child. Because of the low passage of pantoprazole and omeprazole into breast milk, their short half-life, the use of PPIs in pediatrics and the low risk of adverse effects, breastfeeding can be continued with a PPI. If you have had good relief with omeprazole I would advise you to continue with it. If it has not been as effective as pantoprazole, you may want to return to pantoprazole. As for clonazepam, it would have a possible impact in children, the risk/benefit ratio would have to be evaluated. However, the use of benzodiazepines occasionally or for a short period of time during breastfeeding may be considered. Less lipophilic molecules with short or intermediate half-lives and no active metabolites, such as lorazepam or oxazepam, should be preferred to reduce exposure to the child. This should be discussed with your doctor. Do not hesitate to contact me if you have any further questions or concerns about your treatments and breastfeeding. Sami Soltan, pharmacist Cité Mirabel Pharmacy 450-508-3330

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