Hello, I heard that grapefruit juice could interact with certain medications...is celebrex arava methotrexate correct?

Question

Excuse me, I had completely forgotten that I also take 5mg of prednisone every day for arthritis...am I still correct about the grapefruit....a big thank you to you and I apologize again!!

Véronique Gagnon · Accepted Answer

Hello, In fact, consuming grapefruit or its juice can cause an increase or decrease in the effect of certain medications. This is because grapefruit contains compounds that inhibit the processing and elimination mechanism of certain drugs in the gut. The consequences of the interaction vary depending on the patient and the drug used. Seville oranges, limes, and grapefruits may also have this interaction. As for the specific drugs you are asking about, there is nothing to worry about, this interaction does not apply with Celebrex (celecoxib), Arava (leflunomide) or Methotrexate There is no problem with prednisone and grapefruit either. If you have any other questions about this, feel free to ask on this platform or your pharmacist, that's what we're here for!