I am taking Apo sulfatrim antibiotics for sinusitis and I have a headache. Can I take Advil or Tylenol?

Good evening, there is no interaction between taking apo-sulfatrim and Advil or Tylenol; you can take it if you have a headache. Note that some people may experience stomach upset while taking apo-sulfatrim. Advil can also cause stomach upset. It is best to avoid taking these two medicines on an empty stomach.