Can taking multiple high-dose anti-seizure medications make taking narcotics (any kind) bring no relief, even if we have never taken them before?

33-year-old woman7 years ago

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33-year-old woman · 7 years ago

Rx: Vimpat, Diacomit, Aptiom, Keppra, Fycompa, Lithium. ATCD: B type II, drug-resistant epilepsy.

Alexandre Chagnon · 7 years ago

Good morning, Madam,

Alexandre Chagnon · 7 years ago

Some drugs in the anticonvulsant class are known to reduce the effectiveness of certain opioids by accelerating their elimination. This is the case with Aptiom (eslicarbazepine), which can reduce the effectiveness of codeine, hydrocodone and fentanyl.

Alexandre Chagnon · 7 years ago

Is this a familiar situation for you?

33-year-old woman · 7 years ago

Yes, with Dilaudid and Morphine. I don't see any improvement. Also, as you can see I am on Lithium, so I can't use NSAIDs and I don't know what to take for the pain that has been going on since January 2018. Do you have a suggestion?

33-year-old woman · 7 years ago

The related diagnosis is a medial collateral and patellar tendon sprain.

Alexandre Chagnon · 7 years ago

Thank you for these details.

Alexandre Chagnon · 7 years ago

Are you taking Tylenol and doing physical therapy? These are probably the best options for you at this point.

Alexandre Chagnon · 7 years ago

Have a nice day,

Alexandre Chagnon · 7 years ago

Alexandre Chagnon, pharmacist

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