Hello,Both medications are compatible; they can be taken safely at the same time.Since Advil is often taken for headaches, just make sure that the headaches are not due to Concerta (daily headaches, worse a few hours after taking the medication, ceasing on days when the medication is forgotten)! If this is the case, you can discuss solutions with your family pharmacist.We hope to have answered your questions!Stéphane Villeneuve, pharmacist