Can nitroglycerin damage the heart?

Question

Hello to you! I have heard that if a person takes too much nitroglycerin because they are known to have angina or simply to lower their blood pressure, of course with the help of a health professional, it could be harmful to their heart? Very helpful and thank you so much!

Naji-tom Samaha · Accepted Answer

Hello Ma'am, nitroglycerin is indeed indicated for the treatment of angina (a primary symptom of which is chest pain). It comes in several forms, including take-as-needed forms such as nitro mouth spray, injectable form or sublingual tablet. Among other things, it can help dilate small blood vessels in the heart to relieve pain as needed, such as if someone is experiencing pain after shoveling snow or something. Frequent use of this type of product is indeed a problem because it indicates a poorly controlled condition. Also, nitroglycerin can dilate other blood vessels and decrease blood pressure. It does not damage the heart, per se. For those requiring nitro often, time-release products such as the patches (or nitrate tablets) you refer to are suggested. However, if the body is exposed to nitroglycerin on a sustained basis, it can cause tolerance, meaning that the body responds less well to the product. In an effort to avoid this, people who need to use the patch should not wear it more than 12 hours a day. For example, if they apply a patch at 8 a.m., they should remove it at 8 p.m. Conversely, if they apply it at 8pm before going to sleep, they should remove it at 8am the next day and not put another one on until the next night. I hope this has been helpful, please don't hesitate if you have any further questions! Cordially, Tom Samaha, pharmacist It made me happy!