- be an adult with moderate to severe immunosuppression due to an underlying condition or treatment of the same (regardless of vaccination status)
- 60 years of age or older, not adequately vaccinated (less than 2 doses) or not protected against COVID-19;
- 18 years of age or older, not adequately vaccinated (less than 2 doses) or not protected against COVID-19, and have any of the following conditions:
o hemoglobinopathy,
o obesity with a body mass index greater than or equal to 35
o uncontrolled diabetes,
o moderate chronic renal failure,
o mild to moderate hepatic impairment
o uncontrolled hypertension,
o cardiovascular and atherosclerotic disease,
o chronic respiratory disease (e.g. chronic obstructive pulmonary disease or moderate to severe asthma);
- be a pregnant woman and have at least one condition listed above and be inadequately vaccinated (less than 2 doses) or unprotected against COVID-19, after discussion with a pharmacist or the health care professional following the pregnancy
- be an adolescent weighing at least 40 kg (88 lbs) with at least one condition listed above and not adequately vaccinated (less than 2 doses) or not protected against COVID-19, after discussion with a medical specialist or experienced health care worker
- exceptionally, be an adequately protected or vaccinated adult at very high risk of complications from COVID-19 (e.g., very advanced age, multiple comorbidities from the above list, especially if uncontrolled, and poor protection against the circulating variant despite a complete vaccination regimen), after discussion with a medical specialist or experienced health care worker