How long do the withdrawal symptoms of mirtazapine and trazodone last? How long does it take for zoloft to start working or taking effect?

30-year-old woman6 years ago
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a day

30-year-old woman · 6 years ago
Anxiety (tag) insomnia depression , xarelto for clots because embolism
30-year-old woman · 6 years ago
I see my doctor again in 2 days, but I'm not sure if I'm going to be able to do it.
Alexandre Chagnon · 6 years ago
Withdrawal from trazodone is very dose dependent. What dose were you taking? Excessive sweating, sleep disturbances and palpitations may take a few days to 2 weeks to completely disappear.
Alexandre Chagnon · 6 years ago
Finally, the time it takes for Zoloft (sertraline) to start working depends on the dose initially prescribed and the rate of dose increase. The faster Zoloft reaches doses considered "on target," the faster you will feel the effects. Knowing the pattern of switching from mirtazapine to Zoloft, I could answer your question.
30-year-old woman · 6 years ago
I was taking 75 mg of trazodone. mirtazapine went from 30 mg to 15 from Nov. 16 to 22. then 7 mg for 7 days and finished. zoloft I've been taking for 6 days at 25 mg every night and my doctor increased it to 50 mg after 7 days and 75 mg another week later.
30-year-old woman · 6 years ago
so cross weaning
Alexandre Chagnon · 6 years ago
Thank you very much for the information.
Alexandre Chagnon · 6 years ago
It is certain that by stopping the Trazodone 75mg "cold turkey", you were suffering from withdrawal symptoms. However, considering that it has been 7 days since the drug was discontinued, the symptoms should disappear over the next 3 to 7 days or so.
Alexandre Chagnon · 6 years ago
The "cross-over" from mirtazapine to sertraline is quite rapid, so you should feel the effects of Zoloft in about 2 to 3 weeks. The full effect could appear in 4 to 8 weeks. It is very relevant that you have been prescribed Ativan while waiting for your new medication to take effect.
Alexandre Chagnon · 6 years ago
Does this answer your question?
30-year-old woman · 6 years ago
Yes, thank you! So my insomnia will also disappear with time I guess
30-year-old woman · 6 years ago
And also last question, why does it take so long for an antidepressant to take effect?
Alexandre Chagnon · 6 years ago
Exactly! They are also more likely to disappear when the anxiety is well controlled.
Alexandre Chagnon · 6 years ago
For the time it takes for the antidepressant to take effect, it is thought that the effect of this type of medication is primarily caused by a remodeling of the neurotransmitter receptors in the brain. In other words, antidepressants change the amount of neurotransmitters in the brain fairly quickly, but this is not what would cause the majority of the effects of these drugs. Of course, the remodeling of the receptors happens much more slowly, which causes the delay.
Alexandre Chagnon · 6 years ago
Is my answer clear enough?
30-year-old woman · 6 years ago
Yes it's perfect!

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